PHENIX is a software
suite for the automated determination of macromolecular structures
using X-ray crystallography and other methods.
PHENIX: a comprehensive Python-based
system for macromolecular structure solution.
P. D. Adams, P. V. Afonine, G. Bunkóczi, V. B. Chen, I. W. Davis, N. Echols,
J. J. Headd, L.-W. Hung, G. J. Kapral, R. W. Grosse-Kunstleve, A. J. McCoy,
N. W. Moriarty, R. Oeffner, R. J. Read, D. C. Richardson, J. S. Richardson,
T. C. Terwilliger and P. H. Zwart.
Acta Cryst. D66, 213-221 (2010).
Download the latest official release (1.8.2)
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|Using PHENIX (release 1.8.2):
||Full Documentation PDF
|- Assessing data quality with phenix.xtriage|
|- Automated structure solution with AutoSol|
|- Automated molecular replacement with AutoMR|
|- Automated model building and rebuilding with AutoBuild|
|- Automated ligand fitting with LigandFit|
|- Structure refinement with phenix.refine|
|- Generation of ligand coordinates and restraints with elbow|
|- The PHENIX Graphical User Interface|
The PHENIX system also includes SOLVE/RESOLVE, Phaser, the CCI Applications (phenix.xtriage, phenix.refine, elbow and many more), components from Molprobity, and the Computational Crystallography Toolbox in a Python
|Funding for PHENIX:
Protein Structure Initiative
(NIH General Medical Sciences)
The PHENIX system also can be used for neutron crystallography. NIH funding supports the development of this capability through a grant to Paul Langan (Los Alamos National Laboratory) and Paul Adams. See the Macromolecular Neutron Crystallography Consortium site for more details. Citation for neutron structure refinement in Phenix: Adams PD, Mustyakimov M, Afonine PV, Langan P: Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules. Acta Cryst. 2009, D65:567-573.||