Dear Consortium Members,

The 2025 Spring Phenix Developers Meeting is this week March 17-19, 2025 in Santa Fe, NM and online.

The Phenix Developers will host a series of talks on Monday and Tuesday, March 17 & 18. And, we will host an Industry Roundtable discussion on Wednesday, March 19 in the morning (USA Mountain Time). This is a chance to ask questions and discuss any issues directly with the Developers. 

The agenda posted on the workshop website (login:workshop, pswd:phenix3py) shows the complete schedule for those attending in person. 

Monday, March 17 – Talks
  • 09:00 – 09:05 AM Paul D. Adams, Introduction
  • 09:05 – 09:30 AM Dorothee Liebschner, Current status of DiSCaMB integration/Overview of MicroED models.
  • 09:30 – 09:55 AM Paulina Dominiak, Aspherical scattering factors in refinement of biomacromolecules
  • 09:55 – 10:20 AM Malgorzata Biczysko, Quantum refinement with machine learning: AQuaRef 
  • 10:20 – 10:35 AM Break
  • 10:35 – 11:00 AM Tom Terwilliger, Is there a best assignment of side-chain alternative conformations to conformers?
  • 11:00 – 11:25 AM David Case, Creating and evaluating ensemble atomic models
  • 11:25 – 11:45 AM Billy Poon, Phenix updates
  • 11:45 - 12:10 PM Jane Richardson, Opportunities and concerns in RNA modeling
  • 12:10 – 12:30 PM Christopher Schlicksup, Exploration of per-atom real space refinement weight
Tuesday, March 18 – Talks (USA Mountain Time)
  • 09:00 – 09:05 AM Paul D. Adams, Welcome
  • 09:05 – 09:30 AM Laura Pacoste, Developing electron diffraction methods to probe oxidation states in metalloenzymes (virtual)
  • 09:30 – 09:55 AM Airlie McCoy, phasertng updates (virtual)
  • 09:55 – 10:20 AM Pavel Afonine, I. Nuances, New Tools, and Methods for Visualizing and Validating Subtle Structural Details.II. Atomic Model Refinement Gets More Accurate: Combining Aspherical Density Models with Quantum-Based Restraints
  • 10:20 – 10:45 AM Alisia Fadini, AlphaFold as a Prior: Guiding Protein Structure Prediction Using Experimental Data with ROCKET
  • 10:45 – 11:00 AM Break
  • 11:00 – 11:25 AM Oleg Sobolev, Automatically Finding the Best Reference Model
  • 11:25 – 11:50 AM Nigel W. Moriarty, Paradigm Shift for Ligands in Phenix - Part Deux
  • 11:50 – 12:15 PM Christopher Williams, Further details of low-pLDDT AlphaFold2 predictions
Wednesday, March 19 – Phenix Industry Session
  • 9:00 AM – 12:00 PM   Industry Roundtable – conference of developers and industry to discuss the future directions of Phenix. This session will be devoted to a discussion of AlphaFold/RosettaFold and future directions. Industry consortium members are encouraged to attend. 
The Zoom information is below.

We look forward to having you join the meeting and discussion.

Thank you,
Ashley

Join Zoom Meeting
https://lbnl.zoom.us/j/91935895632?pwd=apavpMaMGbJ0FLXw9Q8rCECI8iAyng.1

Meeting ID: 919 3589 5632
Passcode: 730330

---

One tap mobile
+12133388477,,91935895632# US (Los Angeles)
+16692192599,,91935895632# US (San Jose)

---

Dial by your location
• +1 213 338 8477 US (Los Angeles)
• +1 669 219 2599 US (San Jose)
• +1 669 900 6833 US (San Jose)
• +1 206 337 9723 US (Seattle)
• +1 253 215 8782 US (Tacoma)
• +1 346 248 7799 US (Houston)
• +1 602 753 0140 US (Phoenix)
• +1 720 928 9299 US (Denver)
• +1 971 247 1195 US (Portland)
• +1 470 250 9358 US (Atlanta)
• +1 470 381 2552 US (Atlanta)
• +1 646 518 9805 US (New York)
• +1 646 558 8656 US (New York)
• +1 651 372 8299 US (Minnesota)
• +1 786 635 1003 US (Miami)
• +1 267 831 0333 US (Philadelphia)
• +1 301 715 8592 US (Washington DC)
• +1 312 626 6799 US (Chicago)

Meeting ID: 919 3589 5632

Find your local number: https://lbnl.zoom.us/u/adUP3eF75H

---

Join by SIP
• 91935895632@zoomcrc.com

---

Join by H.323
• 144.195.19.161 (US West)
• 206.247.11.121 (US East)
• 115.114.131.7 (India Mumbai)
• 115.114.115.7 (India Hyderabad)
• 159.124.15.191 (Amsterdam Netherlands)
• 159.124.47.249 (Germany)
• 159.124.104.213 (Australia Sydney)
• 159.124.74.212 (Australia Melbourne)
• 64.211.144.160 (Brazil)
• 159.124.168.213 (Canada Toronto)
• 159.124.196.25 (Canada Vancouver)
• 170.114.194.163 (Japan Tokyo)
• 147.124.100.25 (Japan Osaka)

Meeting ID: 919 3589 5632
Passcode: 730330


If you would like to add company members to subscribe to our industry partners listserv, please email industry-join@phenix-online.org with “subscribe” (no quotes) as the subject line and nothing in the body. By subscribing, you will receive information about developer meetings, workshops, and industry-focused sessions that happen a few times a year. If you no longer want to receive these emails, you may choose to use "unsubscribe" in the subject line. This is not a discussion listserv. If you have software questions, please email help@phenix-online.org.
  


Ashley Dawn (she/her/hers) 
Molecular Biophysics & Integrated Bioimaging (MBIB)
Lawrence Berkeley Laboratory
510-486-5455