Dear Consortium Members,
The* 2025 Spring Phenix Developers Meeting
https://phenix-online.org/workshops/mar-2025-lanl/index.html* http:///will
be held *March 17-19, 2025 *in Santa Fe, NM and online.
The Phenix Developers will host a series of talks on Monday and
Tuesday, March 17 & 18. And, we will host an *Industry Roundtable
discussion on Wednesday, March 19* in the morning (USA Mountain Time). This
is a chance to ask questions and discuss any issues directly with the
Developers.
The agenda posted on the workshop website
https://phenix-online.org/workshops/mar-2025-lanl/index.html
(login:workshop, pswd:phenix3py) shows the complete schedule for those
attending in person.
Monday, March 17 – Talks
- 09:00 – 09:05 AM Paul D. Adams, Introduction
- 09:05 – 09:30 AM Paulina Dominiak, Aspherical scattering factors in
refinement of biomacromolecules
- 09:30 – 09:55 AM Dorothee Liebschner, Current status of DiSCaMB
integration/Overview of MicroED models.
- 09:55 – 10:20 AM Billy Poon, Phenix updates.
- 10:20 – 10:35 AM Break
- 10:35 – 11:00 AM Oleg Sobolev, Reference Model Restraints
- 11:00 – 11:25 AM Tom Terwilliger, Is there a best assignment of
side-chain alternative conformations to conformers?
- 11:25 – 11:50 AM Malgorzata Biczysko, Quantum refinement with
machine learning: AQuaRef
- 11:50 – 12:15 PM Jane Richardson, Opportunities and concerns in RNA
modeling
Tuesday, March 18 – Talks
- 09:00 – 09:05 AM Paul D. Adams, Welcome
- 09:05 – 09:30 AM Laura Pacoste, title TBD (virtual)
- 09:30 – 09:55 AM Airlie McCoy, phasertng updates
- 09:55 – 10:20 AM Pavel Afonine, I. Nuances, New Tools, and Methods
for Visualizing and Validating Subtle Structural Details.II. Atomic Model
Refinement Gets More Accurate: Combining Aspherical Density Models with
Quantum-Based Restraints.
- 10:20 – 10:35 AM Alicia Fadini, AlphaFold as a Prior: Guiding
Protein Structure Prediction Using Experimental Data with ROCKET
- 10:35 – 11:00 AM Break
- 11:00 – 11:25 AM David Case, Creating and evaluating atomic models
using Xray and cryoEM data
- 11:25 – 11:50 AM Nigel W. Moriarty, Paradigm Shift for Ligands in
Phenix - Part Deux
- 11:50 – 12:15 PM Christopher Williams, Further details of low-pLDDT
AlphaFold2 predictions
Wednesday, March 19 – Phenix Industry Session
- 9:00 AM – 12:00 PM Industry Roundtable – conference of developers
and industry to discuss the future directions of Phenix. This session will
be devoted to a discussion of AlphaFold/RosettaFold and future directions.
Industry consortium members are encouraged to attend.
The Zoom information is below my signature.
We look forward to having you join the meeting and discussion.
Thank you,
Ashley
Ashley Dawn (she/her/hers)
Program Manager, Phenix Industrial Consortium https://phenix-online.org/
Molecular Biophysics & Integrated Bioimaging (MBIB
https://biosciences.lbl.gov/mbib/)
Lawrence Berkeley Laboratory
510-486-5455
*If you would like to add company members to subscribe to our industry
partners listserv, please email [email protected]