<html><head><meta charset="UTF-8"><meta http-equiv="content-type" content="text/html; charset=us-ascii"></head><body style="overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div class="shell" lang="en-US" style="text-align: left; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; background-color: rgb(235, 235, 235);">Dear Colleagues,</div><div class="shell" lang="en-US" style="text-align: left; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; background-color: rgb(235, 235, 235);"><br></div><div class="shell" lang="en-US" style="text-align: left; text-indent: 0px; background-color: rgb(235, 235, 235);">The Cold Spring Harbor Macromolecular Crystallography course will take place October 13-29th this year (pleased see below for more details). This comprehensive course is an outstanding place to learn both the theoretical and practical aspects of macromolecular crystallography. There are extensive lectures and practical sessions from world recognized experts in crystallization, data collection, data processing, structure solution, refinement, and validation. The goal of the course is for researchers who have had some exposure to structural biology to become experts in crystallography. This is an experience in macromolecular crystallography learning that cannot be found anywhere else, and the student/teacher ratio is often 1:1.<br></div><div class="shell" lang="en-US" style="text-align: left; text-indent: 0px; background-color: rgb(235, 235, 235);"><br></div><div class="shell" lang="en-US" style="text-align: left; text-indent: 0px; background-color: rgb(235, 235, 235);"><div class="shell" lang="en-US">Please follow the link below to the course web site. In particular, please note the information about the various fellowships, scholarships, and stipends that are available. </div><div class="shell" lang="en-US"><br></div><div class="shell" lang="en-US">If anyone has any questions please send me an e-mail, and we will be happy to answer all queries.</div><div class="shell" lang="en-US"><br></div><div class="shell" lang="en-US"> Paul Adams</div></div><div class="shell" lang="en-US" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: auto; text-align: center; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; background-color: rgb(235, 235, 235);"><br></div><div class="shell" lang="en-US" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; 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font-size: 34px; color: rgb(248, 245, 149); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold; font-style: normal;">Macromolecular Crystallography</a></p><p align="center" style="margin: 0px; padding: 0px; text-align: center;"><span style="font-size: 24px; color: rgb(255, 255, 255); font-weight: bold; font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">October 13 - 29, 2024</span></p><p align="center" style="margin: 0px; padding: 0px; text-align: center;"><span style="font-size: 24px; color: rgb(255, 255, 255); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">Applications Due: July 15</span></p></td></tr></tbody></table></td></tr></tbody></table><table class="layout layout--heading layout--1-column" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed; min-width: 100%;"><tbody><tr><td class="column column--1 scale stack" align="center" valign="top" style="width: 610px;"><table class="text text--heading text--padding-vertical" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed;"><tbody><tr><td class="text_content-cell content-padding-horizontal" align="center" valign="top" style="-webkit-font-smoothing: antialiased; text-align: center; font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(113, 122, 128); font-size: 24px; line-height: 1.2; display: block; overflow-wrap: break-word; font-weight: bold; padding: 10px 20px;"><p align="left" style="margin: 0px; padding: 0px; text-align: left;"><span style="color: rgb(106, 144, 105);">Instructors</span></p></td></tr></tbody></table></td></tr></tbody></table><table class="layout layout--1-column" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed; min-width: 100%;"><tbody><tr><td class="column column--1 scale stack" align="center" valign="top" style="width: 610px;"><table class="text text--padding-vertical" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed;"><tbody><tr><td class="text_content-cell content-padding-horizontal" align="left" valign="top" style="-webkit-font-smoothing: antialiased; line-height: 1.5; text-align: left; font-family: Calibri, Helvetica, Arial, sans-serif; color: rgb(54, 73, 95); font-size: 14px; display: block; overflow-wrap: break-word; padding: 10px 20px;"><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Paul Adams,</span><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;"> Lawrence Berkeley National Laboratory</span></p><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-weight: bold; font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">Dorothee Liebschner</span><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">, Lawrence Berkeley National Laboratory</span></p><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Janet Newman, </span><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">UNSW, Australia</span></p><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">James Pflugrath,</span><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;"> Rigaku Americas Corporation (ret.), Texas</span></p><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(106, 144, 105); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-style: italic; font-weight: bold;">Co-Instructor</span></p><p style="margin: 0px; padding: 0px;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-weight: bold; font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;">Tom Peat,</span><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif;"> UNSW, Australia</span></p></td></tr></tbody></table></td></tr></tbody></table><table class="layout layout--heading layout--1-column" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed; min-width: 100%;"><tbody><tr><td class="column column--1 scale stack" align="center" valign="top" style="width: 610px;"><table class="text text--heading text--padding-vertical" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed;"><tbody><tr><td class="text_content-cell content-padding-horizontal" align="center" valign="top" style="-webkit-font-smoothing: antialiased; text-align: center; font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(113, 122, 128); font-size: 24px; line-height: 1.2; display: block; overflow-wrap: break-word; font-weight: bold; padding: 10px 20px;"><p align="left" style="margin: 0px; padding: 0px; text-align: left;"><span style="color: rgb(106, 144, 105);">Topics Covered</span></p></td></tr></tbody></table></td></tr></tbody></table><table class="layout layout--1-column" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed; min-width: 100%;"><tbody><tr><td class="column column--1 scale stack" align="center" valign="top" style="width: 610px;"><table class="text text--padding-vertical" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed;"><tbody><tr><td class="text_content-cell content-padding-horizontal" align="left" valign="top" style="-webkit-font-smoothing: antialiased; line-height: 1.5; text-align: left; font-family: Calibri, Helvetica, Arial, sans-serif; color: rgb(54, 73, 95); font-size: 14px; display: block; overflow-wrap: break-word; padding: 10px 20px;"><ul style="padding: 0px; margin: 0px 0px 0px 40px;"><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Basic Diffraction Theory</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Structure Presentation</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Coordinate Deposition</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Structure Validation</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Model Building and Refinement</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Electron Density Maps Improvement</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Using Predicted Models in Structure Solution and Completion</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Protein Structure Prediction</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Structure Solution by Experimental Phasing Methods (SAD, MAD, MIR, and others) and Molecular Replacement</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Data Collection and Processing</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Synchrotron X-ray Sources and Optics</span></li><li style="padding: 0px; margin: 0px; font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;"><span style="font-size: 16px; color: rgb(74, 101, 74); font-family: "Century Gothic", Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Crystallization (Proteins, Nucleic Acids, Complexes and Membrane Proteins)</span></li></ul></td></tr></tbody></table></td></tr></tbody></table><table class="layout layout--1-column" width="100%" border="0" cellpadding="0" cellspacing="0" style="table-layout: fixed; 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<meta charset="UTF-8"><div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="text-align: start; text-indent: 0px; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="text-align: start; text-indent: 0px; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="text-align: start; text-indent: 0px; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div dir="auto" style="text-align: start; text-indent: 0px; overflow-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;"><div style="caret-color: rgb(34, 34, 34); color: rgb(34, 34, 34); letter-spacing: normal; text-transform: none; white-space: normal; word-spacing: 0px; text-decoration: none; -webkit-text-stroke-width: 0px; font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);"><span style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica;">--</span></div><div style="background-color: rgb(255, 255, 255);">Paul Adams (he/him/his)<br>Associate Laboratory Director for Biosciences, LBL (https://biosciences.lbl.gov) <br>Principal Investigator, Computational Crystallography Initiative, LBL (http://cci.lbl.gov) <br>Vice President for Technology, the Joint BioEnergy Institute (http://www.jbei.org) <br>Principal Investigator, ALS-ENABLE, Advanced Light Source (http://als-enable.lbl.gov) <br>Laboratory Research Manager, ENIGMA Science Focus Area (http://enigma.lbl.gov) <br>Adjunct Professor, Department of Bioengineering, UC Berkeley (http://bioeng.berkeley.edu) <br>Member of the Graduate Group in Comparative Biochemistry, UC Berkeley (http://compbiochem.berkeley.edu) <br><br>Building 91, Room 410<br>Building 978, Room 4126<br>Tel: 1-510-486-4225<br>http://cci.lbl.gov/paul <br>ORCID: 0000-0001-9333-8219<br><br>Lawrence Berkeley Laboratory<br>1 Cyclotron Road<br>BLDG 91R0183<br>Berkeley, CA 94720, USA.<br><br>Executive Assistant: Michael Espinosa [ MEEspinosa@lbl.gov ][ 1-510-333-6788 ]<br>Phenix Consortium: Ashley Dawn [ AshleyDawn@lbl.gov ][ 1-510-486-5455 ]<br></div><div style="caret-color: rgb(34, 34, 34); color: rgb(34, 34, 34); letter-spacing: normal; text-transform: none; white-space: normal; word-spacing: 0px; text-decoration: none; -webkit-text-stroke-width: 0px; font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);"><font color="#000000" face="Helvetica">--</font></div></div></div></div></div></div></div></div></div>
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