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Hi,<br>
<br>
there is a number of cases when increase in Rfree is expected and
normal:<br>
- you just started refinement using a new test set;<br>
- the starting structure is under-refined,<br>
etc.<br>
<br>
None of the above seems to be yours, which to me indicates a problem
with your refinement strategy.<br>
<br>
Pavel<br>
<br>
On 2/6/12 5:39 PM, Dialing Pretty wrote:
<blockquote
cite="mid:1328578749.57869.YahooMailNeo@web121701.mail.ne1.yahoo.com"
type="cite">
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new roman, new york, times, serif;font-size:12pt"><br>
<div style="font-family: times new roman,new york,times,serif;
font-size: 12pt;">Dear All,<br>
<br>
I did a Phenix refine,Rwork increases from 0.2366 to 0.2455,
Rfree increases from 0.2363 to 0.2668, but the Molprobity
analysis results were pretty satisfactory.<br>
<br>
Do you think whether my results are reliable or not?<br>
<br>
Cheers,<br>
<br>
Dialing<br>
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