<div>Hi all,</div>
<div>in the final stages of refining a structure, I would like to optimize the restraint weights for geometry and B factors.</div>
<div>It seems to work fine for geometry by defining "refinement.target_weights.wxc_scale=1.0".</div>
<div>However, when the respective definition for B-factors does not seem to have an impact at all.</div>
<div>I tried both:</div>
<div>"refinement.target_weights.wxu_scale=2.0" in the parameter file or</div>
<div>"wxu_scale=2.0" in the command line.</div>
<div> </div>
<div>The main reason why I try to fiddle around with the B-weights is that coot gives me a whole bunch of red bars in the Temperature factor variance analysis...</div>
<div> </div>
<div>I am using phenix 1.3d (downloaded past Sunday), mac-intel-osx, osx-10.4.10</div>
<div> </div>
<div>Any ideas?</div>
<div> </div>
<div>Cheers</div>
<div>Jan</div>