[phenixbb] Scientist Antibody Production at the Institute for Protein Innovation in Boston, USA

[Christopher Bahl]

Scientist Antibody Production

Reports to the Head of Biological Discovery, Dr. Rob Meijers

The Institute for Protein Innovation (IPI) is a nonprofit research
organization advancing protein science to accelerate research and improve
human health. Located on the Harvard Medical School campus in the Boston
Longwood Medical Area, IPI is pioneering a new way of doing science that
uniquely combines the freedom of academia with the high-throughput scaling
of industry to take on transformative projects.  IPI has built a robust
platform and a repository of synthetic antibodies and other protein tools
to share with the biomedical community through licensing and collaboration.
The Institute’s deep protein expertise, collaborative spirit and
fit-for-purpose antibodies are powering new biomedical and therapeutic
discoveries for academic and industrial researchers worldwide.


Job Overview

IPI’s flagship project, the “Antibody Initiative,” aims to create
well-characterized, synthetic antibodies against human cell surface
receptors and their ligands, particularly those that are traditionally
difficult to target. These antibodies may have high therapeutic and
diagnostic potential but will also serve to enable basic biological
discovery.

The Scientist, Antibody Production will play an essential role in the
high-throughput production, characterization and formulation of synthetic
antibodies for this Initiative and other key IPI projects. Specifically,
the successful candidate will join the Protein Group, a dynamic team
generating high-quality antibodies and developing new technologies for
conjugation.

Having completed a doctorate in protein chemistry, the successful candidate
will bring to the job experience in mammalian expression, purification and
reagent-grade preparation of glycoproteins. The candidate will be adept in
quality control and process management and reliably provide detailed
documentation on experiments completed.

The Scientist will work in close collaboration with the other Antibody
Initiative team members and enjoy the opportunity to contribute to a wide
array of novel biological discovery projects. As this position is highly
collaborative, strong communication skills are needed. The Scientist will
engage with outside collaborators, translate their biological questions
into novel protein reagents and share these reagents with the larger
research community through abstracts, presentations and publications.


Responsibilities and Duties

-Express, purify, and characterize glycoproteins from mammalian cells
-Leverage robotics and automation to increase the quality and throughput of
antibody production at IPI
-Formulate and package antibodies for use by collaborators and customers
-Supervise research associates and coordinate with other scientists to
ensure efficient, high-quality antibody production
-Actively lead the experimental design and data production for
collaborations and scientific publications
-Participate in meetings and conferences to engage and recruit outside
research groups to participate in the Antibody Initiative


Qualifications

-PhD degree in mammalian protein expression, protein biochemistry, or
structural biology
-Well acquainted with best practices in cell culture and reagent production
-Ability to work in a fast-paced, intellectually challenging environment
-Enthusiastic team member with a strong commitment to mission and a desire
to conduct impactful science
-Good organizational and documentation skills
-The ideal candidate will have recently completed a PhD and have a desire
to explore a more entrepreneurial position

IPI is an independent 501(3)(c) nonprofit research organization and an
equal opportunity employer. The Institute celebrates diversity and is
committed to creating an inclusive environment for all employees. If
interested, please email your resume to .

-- 

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