[phenixbb] 2 positions around XChem-related compound design
Frank von Delft
frank.vondelft at sgc.ox.ac.uk
Wed Apr 24 08:29:38 PDT 2019
Dear all, I have two open to work on fragment/XChem-related methodology
for structure-based compound design.
Team Leader (applications close next *Weds 1st May*): full ad here
<https://www.thesgc.org/careers/oxford/sgc-oxford-team-leader-xchem>,
summary:
/We are recruiting an experienced computational chemist or
scientific programmer, to head the Fragalysis project for automating
fragment hit progression, part of the XChem collaboration between
SGC and Diamond... The //Fragalysis
<https://fragalysis.diamond.ac.uk/>//project leader will be tasked
with converting the existing proof-of-concept tool into a
production-level system that is routinely usable for analysing XChem
results and designing and acquiring follow-up compounds. This will
entail setting the scientific direction and priorities of the
project through close and continuous interaction with expert and
novice users; coordinating a growing team of scientific programmers
and contractors; liaising with and expanding a wide and
international set of collaborators and contributors; securing
further funding for the project; helping supervise students; and
developing specific methodologies of their own./
Postdoc (closing *Weds 15th May*): full advert here
<https://www.thesgc.org/careers/oxford/sgc-oxford-postdoctoral-research-scientist-structure-based-drug-design>,
this is a summary:
/This role will be tasked with the design and acquisition of
follow-up compounds based on fragment screening hits from the Target
Enabling Package (//www.thesgc.org/tep
<http://www.thesgc.org/tep>//) and Ultra-DD (//www.ultra-dd.org
<http://www.ultra-dd.org>//) programs. The successful candidate will
coordinate experimental validation of the newly designed compounds
with collaborating scientists in order to progress them towards
potent molecules.
/
Cheers
Frank
--
Prof Frank von Delft
Associate Professor Principal Investigator: Protein Crystallography
Structural Genomics Consortium
Oxford University
+44 1865 617583 (office: W,F)
Principal Beamline Scientist: I04-1
Diamond Light Source
+44 1235 778997 (office: M,T,T)
+44 7471 026103 (mobile)
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