[phenixbb] Please attend a workshop on Measurement and Interpretation of Diffuse Scattering in X-Ray Diffraction for Macromolecular Crystallography
sweet at bnl.gov
Wed Mar 8 06:38:58 PST 2017
Driven by recent advances in this field we will hold a workshop to discuss
it. The workshop will be on Monday, May 15, 2017 at Brookhaven Nat'l
Laboratory, and will be affiliated with the 2017 Users' Meeting for
NSLS-II and the Center for Functional Nanomaterials.
The current draft agenda is on-line here:
Registration for the Workshop and Users' Meeting is here:
A description of the workshop is below.
The Organizers: Robert Sweet (NSLS-II, BNL), Michael Wall (LANL), Nozomi
Ando (Princeton University), James S. Fraser (University of California,
San Francisco), George N. Phillips, Jr. (Rice University)
For answers to questions, please contact Wall: mewall at lanl.gov or Sweet:
sweet at bnl.gov
X-ray diffraction from macromolecular crystals includes both sharply
peaked Bragg reflections and diffuse intensity between the peaks. The
information in Bragg scattering reflects the mean electron density in the
unit cells of the crystal. The diffuse scattering arises from
correlations in the variations of electron density that may occur from one
unit cell to another, and therefore contains information about collective
motions in proteins.
A major focus of the workshop will be to provide a roadmap to the
acquisition of reliable data by surveying measurement methods and
discussing the increase in measurement accuracy enabled by improved
detectors, experimental methods, and data integration.
Missing from recent results is real information about the behavior of the
molecules being studied that would guide the thinking of biochemists and
biologists. To discuss these and their relative merits will be a second
major focus of the workshop.
The charge to this workshop will be to provide a roadmap to efforts that
will provide the biological understanding we believe is hidden in the
Robert M. Sweet E-Dress: sweet at bnl.gov
Deputy Director, LSBR: The Life Science and ^ (that's L
Biomedical Technology Research Center at NSLS-II not 1)
Photon Sciences and Biology Dept
Office and mail, Bldg 745, a.k.a. LOB-5
Brookhaven Nat'l Lab. Phones:
Upton, NY 11973 631 344 3401 (Office)
U.S.A. 631 344 2741 (Facsimile)
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