[phenixbb] Rosetta and disulphides

[Morten Groftehauge]

Well they aren't conserved so I guess I'll have to do some manual
remodelling. The new version of HHPred is nice about building you a quick
homology model to start with though (using Modeller).

Thanks Tom!

On 22 March 2012 00:56, Terwilliger, Thomas C <terwilliger at lanl.gov> wrote:

>  Hi Morten,
>
>  I asked about this...and if your input model has Cys-Cys disulfides and
> the sequence file also has these cysteine residues, then the disulfides
> should be maintained by Rosetta. If that isn't happening, let me know!
>
>  I hope that helps!
> All the best,
> Tom T
>
>  ------------------------------
> *From:* phenixbb-bounces at phenix-online.org [
> phenixbb-bounces at phenix-online.org] on behalf of Morten Groftehauge [
> mortengroftehauge.work at gmail.com]
> *Sent:* Wednesday, March 21, 2012 8:25 AM
> *To:* PHENIX user mailing list
> *Subject:* [phenixbb] Rosetta and disulphides
>
>  Hi phenix-bb'ers,
>
>  Is there anyway to make phenix.mr_rosetta take disulphide bridges into
> account? It's a rather enormous restraint on conformational space after all
> (wait is that a constraint or restraint? I get confused).
>
>  Cheers,
> Morten
>
>  --
> Morten K Grøftehauge, PhD
> Pohl Group
> Durham University
>
>
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>
>


-- 
Morten K Grøftehauge, PhD
Pohl Group
Durham University
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