[phenixbb] phenix and weak data

Nathaniel Echols nechols at lbl.gov
Fri Dec 7 14:17:13 PST 2012


On Fri, Dec 7, 2012 at 1:54 PM, Douglas Theobald <dtheobald at brandeis.edu> wrote:
> Maybe I've misunderstood, but Karplus and Diederichs used phenix in their paper arguing for including weak data.  Whether the benefit they describe is considered cosmetic or non-trivial, it at least appears that including very weak data doesn't hurt.  At least with phenix.

Yes, I forgot to mention this.  I suspect that most other modern
refinement programs, which all use maximum likelihood targets (but
with various differences), would behave similarly.

-Nat


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