[phenixbb] refinement with alternative molecules?
sul2005 at med.cornell.edu
Mon Jan 25 19:09:44 PST 2010
Recently I got a crystal structure of a multiple-molecules protein complex.
There are many protein subunits with the same fold. From the likelihood-weighted
maps by Phenix, I can see two different subunits occupy the same
position. (So I can put the model of either subunit in the same
densities, but some loop regions and the C-terminal tail look
I know Phenix can do occupancy refinement with a residue that has N
alternative conformations. My question is can Phenix do occupancy
refinement with alternative molecules?
The RMSD for two subunits is about 1.3 angstrom. The sequence
identity is about 30%.
Thank you very much!
Su-Chang Lin, Ph.D., Postdoc Associate
Department of Biochemistry
Weill Medical College, Cornell University
Whitney Building, room W-212
1300 York Avenue, New York, NY 10021
More information about the phenixbb