[phenixbb] Beamtime at the ALS

Peter Zwart PHZwart at lbl.gov
Tue Jan 12 14:17:14 PST 2010


Dear All,

January 15, 2010 is the deadline for the March/April 2010 Rapid Access
Proposal cycle.

All Berkeley Center for Structural Biology(BCSB) beamlines are equipped with
ADSC Q315/Q315R detectors, automated sample changers and data collection
software enabling high-throughput crystal screening and data collection.

Remote data collection is available on all BCSB beamlines, providing the
user with the full complement of sample visualization, sample manipulation,
beamline control, data acquisition and data analysis tools exactly as
they would
see them if they were stationed at the beamline.  This enhanced remote
operation
capability is coupled with 22hr onsite support by BCSB staff who are able to
assist immediately with loading additional samples for remote users or
troubleshoot
any issues that might arise. Remote users can furthermore be kept
up-to-date on changes
in ring status via an SMS service
(http://bcsb.als.lbl.gov/wiki/index.php/Ring_Status_Notifications_to_Cell_Phone)

Specific features are summarized below.

Beamlines 8.2.1 and 8.2.2:

To facilitate studies on small crystals, a microdiffractometer was
installed in the beamline 8.2.1 endstation. The new equipment allows
precise sample positioning to within 2 microns, excellent sample
viewing of very small crystals, and an off-axis crystal positioning
stage.

Both beamlines 8.2.1 and 8.2.2 feature a Rigaku sample changer (Actor),
allowing remote operations to now be a routine mode of access for
these beamlines.

Beamlines 5.0.1, 5.0.2, 5.0.3:

The Berkeley Automounter sample handling system has a routine capacity of 96
samples (6 pucks). In a typical high-throughput screening mode, the
mount-to-mount time
is around 2.5 minutes per sample, allowing users to screen a full puck
within 45 minutes.

The sector 5 beamline user stations are equipped with fully
high-adjustable, ergonomically
friendly work stations.

Data analyses in the BCSB is facilitated by software maintained by sbgrid
(http://www.sbgrid.org).  A 16 core linux machine is available for our users
to process their data and solve/refine their structure.

An additional mode of access to the BCSB beamlines is through the
Collaborative Crystallography (CC) Program. Users apply for beamtime
via the general user program, and collaborate with an expert
crystallographer who will conduct the experiments and data reduction
on behalf of the researchers. Depending on the users, structure
solution, model building and refinement can be carried out as well.
Please contact BCSBBeamtime at lbl.gov for more information.

Please visit http://bcsb.lbl.gov/ for more details about the Center
and its beamlines.

To find out more, click on:
http://www.als.lbl.gov/als/quickguide/independinvest.html

We invite you to submit a proposal at:

http://alsusweb.lbl.gov/
Scroll down to "Structural Biology beamines (includes protein SAXS)."
Click on "New Proposal."
If you'd like to apply for May/June 2010 beamtime at the
Advanced Light Source, please submit a General User proposal by
March 15, 2010.

If you have any questions or would like to request open beamtime,
please e-mail BCSBBeamtime at lbl.gov.

Please note that executed user agreements must be received by LBNL
prior to beamtime. Proprietary fees, if applicable, must be received
by LBNL at least five working days prior to scheduled beamtime.


-- 
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P.H. Zwart
Beamline Scientist
Berkeley Center for Structural Biology
Lawrence Berkeley National Laboratories
1 Cyclotron Road, Berkeley, CA-94703, USA
Cell: 510 289 9246
BCSB:     http://bcsb.als.lbl.gov
PHENIX: http://www.phenix-online.org
CCTBX:  http://cctbx.sf.net
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