[phenixbb] Problem with low figure of merit
texshan at gmail.com
Tue Aug 31 08:49:03 PDT 2010
I am new to structure solving. I have a 2.9A dataset for a Seleno crystal of
which i am trying to use Autosol to build an initial map. I used the
settings for a thorough solution, instead of quick. All the other
parameters were set to default settings.
The solution that i got from autosol, gave me the following result
Solution # 1 BAYES-CC: 23.7 +/- 30.9 Dataset #1 FOM: 0.27
Residues built: 238
Side-chains built: 139
Overall model-map correlation: 0.65
Score type: SKEW CORR_RMS
Raw scores: 0.02 0.77
100x EST OF CC: 16.86 32.11
The density modification map matches, quite well with many of my side chains
My question here is , IS THERE A WAY I CAN IMPROVE THE Figure Of Merit , BY
CHANGING ANY PARAMETERS IN PHENIX-AUTOSOL.
I HAVE A HIGH SOLVENT CONTENT IN MY CRYSTAL AND I DID NOT INPUT THAT IN MY
INITIAL PARAMETERS. DOES PHENIX AUTOSOL CONSIDER SOLVENT FLATTENING FOR SUCH
I would appreciate someone's help in this regard
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