[phenixbb] Phaser and anisotropy question
PAfonine at lbl.gov
Thu Sep 10 10:19:31 PDT 2009
> Will this improved anisotropic scaling be implemented in other modules
> of phenix.refine ? If not do you advise using F_ISO, SIGF_ISO from the
> newer version of phaser as the input labels for refinement ?
1) phenix.refine does anisotropic correction, see this paper for more
Acta Cryst. (2005). D61, 850-855. "A robust bulk-solvent correction and
anisotropic scaling procedure". P. V. Afonine, R. W. Grosse-Kunstleve
and P. D. Adams.
and slide #20 here:
2) Improved version of anisotropic scaling suggested by R. Read (more
precisely, a better way of map calculation given high anisotropy) will
be implemented in future. We discussed it but I didn't get a chance yet
to implement it.
3) I do not believe that it is a good idea to use manipulated Fobs in
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