> >> Based on Ian Tickle's >> paper http://journals.iucr.org/d/issues/2007/12/00/gx5119/gx5119.pdf, >> -LLG is slightly more stable and better than Rfree as a refinement >> indicator. > > What does "stable" mean? I think it means that -LLG has less ups and downs at the minimum. I could be wrong. Jianghai