Crystallographic Structure Solution with Phenix

X-ray Crystallography

Click on the boxes in the figure to read an overview of each step. Also see the AlphaFold models in Phenix overview and video tutorials for using AlphaFold models in Phenix.

GUI documentation for most used programs:

• Predict a structure with AlphaFold using PredictModel
• Automated structure determination using AlphaFold models with PredictAndBuild
• Check data quality with Xtriage
• Experimental phasing with AutoSol
• Molecular replacement with Phaser
• Model building with AutoBuild
• Refine your model with phenix.refine
  
• Validation tools in Phenix
• Fit your ligand with LigandFit
• How to generate geometry restraints
• Prepare your model and data for deposition
• Complete list of programs for each structure solution step

Neutron Crystallography

Phenix supports neutron scattering lengths and features joint X-N refinement.

Microcrystal Electron Diffraction (MicroED)

Phenix supports electron scattering factors for neutral atoms.